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Wood Hudson Cancer Research Laboratory Publications: Wood Hudson Cancer Research Laboratory, Inc. has published numerous reports, studies and works. Here is the list of publications authored by our scientists: -------------------------------------------------------------------------------- Published Abstracts: EPA Studies on Rodent Liver and Environmental Chemicals Sub-Lethal Autolysis in Livers of Rats Exposed to Phthalates Expression of Glycosidase Activity in Livers of Male F-344 Rats Given Dietary Phalates After Initiation or in the Two Stage Initiation/Promotion Model abstract Quantification of Glutathione-S-Transferase-P (GST-P) Expression by Image Cytometry in Livers of Fisher 344 Male Rats Given By-Products of Water Chlorination Quantitation of Gammaglutamyl Transpeptidase (GGT) and Glutathione-S-Transferase (GST-P) Expression on livers of Rats Treated with Diethylnitrosamine (DENA) and Phthalate Esters Hyperplastic Nodules (HN) as Putative Preneoplastic Lesions in Dichloroacetic Acid (DCA)-Induced Rat Hepatocarcinogenesis Chronic Toxicity of Dichloroacetic Acid (DCA) in the Male B6C3F1 Mouse abstract Effects of Dichloroacetic Acid (DCA) Apoptosis in Normal, Preneoplastic, and Neoplastic Liver in the Male B6C3F1 Mouse abstract Promotion of Dichloroacetic Acid (DCA) Initiated Hepatocarcinogenesis by Phenobarbital abstract Effects of the Water Chlorination By-Product, Dichloroacetic Acid, (DCA) on Apoptosis In Vitro and In Vivo. Presented at the Joint Meeting of the Kentucky Academy of Science and the Tennessee Academy of Science, Bowling Green, Kentucky, November, 1995. Chronic Toxicity of Dichloroacetic Acid (DCA) in the Male B6C3F1 Mouse. Proceedings of the Fifth Workshop on Mouse Liver Tumors, ILSI Health and Environmental Sciences Institute, Washington, DC, November, 1994. Use of Computerized Image Cytometry in Risk Assesment Research. Presented at the Joint Meeting of the Kentucky Academy of Science and the Tennessee Academy of Science, Bowling Green, Kentucky, November, 1995. -------------------------------------------------------------------------------- Studies on Biomarkers in Human Colon Cancer Quantification of Nuclear Size and Proliferating Cell Nuclear Antigen by Image Cytometry During Neoplastic Progression in Human Colorectal Epithelium Quantitative and Qualitative Differences in Lectin Reactivity (LR) in Normal and Neoplastic Human Colon Tumor-Associated Co-expression of p39 c-jun and p21 ras in Human Colon Carcinomas Co-expression of Ras, Jun, and Fos Oncoproteins in Progressive Stages of Human Colon Cancer abstract Detection of the Sialic Acid-Free D-galactose-B-[1->3]-N-acetyl-D-galactosamine (Gal-GalNAc) Residue in the Normal Colon of Patients with Premalignant and Malignant Colorectal Lesions. Proceedings of the American Association for Cancer Research 37:185, 1996. abstract -------------------------------------------------------------------------------- Studies on Mammary Tumors in Rats Mastopathies Initiated in Female Sprague Dawley Rats by 7,12-Dimethylbenz(a)anthracene Hormonal Regulation of Incidence, Latency and Yield of DMBA Initiated Tumors in Female Sprague Dawley Rats Early Molecular and Cellular Events in 7,12-Dimethylbenz(a)anthracene Induced Rat Mammary Cancer abstract Mammary Lobular Development Associated with Transforming Growth Factor Alpha Expression by Dimethylbenz(a)Anthracene Induced Rat Mammary Tumors. Proceedings of the American Association for Cancer Research 37:43, 1996. abstract Tamoxifen Alters Sub-Cellular Distribution of Lysosomal Enzymes in Carcinogen Treated Rat Liver. Molecular Biology of the Cell, 7:16a, 1996.abstract -------------------------------------------------------------------------------- Studies on Human Breast Cancer Cellular and Molecular Correlates in Human Breast Tumor Progression abstract Glycosidase Activity in Proliferative Mammary Epithelium. Journal of Cell Biology 101:480a, 1985. Evaluation of Molecular Biomarkers and Apoptosis in Human Benign Breast Lesions and Carcinomas. Proceedings of the 10th International Congress of Endocrinology, San Francisco, CA, June, 1996.abstract -------------------------------------------------------------------------------- Studies on Human Prostate Cancer and Benign Prostate Hyperplasia Evaluation of Proliferation and Apoptotic Cell Death Indices in Human Prostate Carcinoma and Benign Prostatic Hyperplasia abstract Occurance of Androgen-Independent Murine Stromal Tumors Following Transplantation of Androgen-Dependent Human Prostatic (PC-82) Xenografts in Nude Mice Use of Archival Tissues to Evaluate Proliferative and Apoptotic Indices in Human Prostate Carcinoma and Benign Prostatic Hyperplasia. Proceedings of the 1996 International Symposium on Biology of Prostate Growth, Washington, DC, March, 1996. abstract -------------------------------------------------------------------------------- Drug Development Studies: Characterization of the Effects of an Aromatase Inhibitor (19-Acetylenic Androstenedione) on Estrogen Levels in Normal Males abstract Early Findings on DNA Fragmentation Assays Using Cultured Cells Artifacts in Apoptotic DNA Fragmentation Assays Caused by Cellular Polyamines and Aminothiols and Their Circumvention abstract -------------------------------------------------------------------------------- Published Articles: In vivo administration of dichloroacetic acid supresses spontaneous apoptosis in murine hepatocytes. Cancer Research 55:3702-3705, 1995. Immunohistochemical analysis of dichloroacetic acid (DCA)-induced hepatocarcinogenesis in male Fisher (F344) rats. Cancer Letters 92:67-76, 1995. Minireview: enzyme-activated inhibitors of steroidal hydroxylases. The Journal of Steroid Biochemistry and Molecular Biology 52:19-34, 1995. Biochemical, pathologic and morphometric alterations induced in male B6C3F1 mouse liver by short-term exposure to dichloroacetic acid. Toxicology Letters, 1995. Immunohistochemical detection of RAS, JUN, FOS, and p53 oncoprotein expression on human colorectal adenomas and carcinomas. Laboratory Investigation 69:674-681, 1993. Correlative microscopy. MSA bulletin 23:219-226, 1993. Quantitative image cytometry of hepatocytes expressing gamma-glutamyl transpeptidase and glutathione S-transferase in diethylnitrosamine-initiated rats treated with phenobarbital and/or phthalate esters. The Journal of Histochemistry and Cytochemistry 40:1105-1115. Studies in red blood cell preservation. 3. A phosphate-ammonium-adenine additive solution. Vox Sang 58:94-99, 1990. Adrenal regulation of mammary tumorigenesis in female Sprague-Dawley rats: incidence, latency, and yield of mammary tumors. Cancer Research 48:3801-3807, 1988. Adrenal regulation of mammary tumorigenesis in female Sprague-Dawley rats: histopathology of mammary tumors. Cancer Research 48:3808-3815, 1988. Quantitative and qualitative immunohistochemical detection of myc and src oncogene proteins in normal, nodule, and neoplastic rat liver. The Journal of Histochemistry and Cytochemistry 36:179-184, 1988. Hepatocyte expression of tumor associated aldehyde dehydrogenase (ALDH-3) and p21 Ras following diethylnitrosamine (DEN) initiation and chronic exposure to di(2-ethylhexyl)phthalate (DEHP). Carcinogenesis 17:1547-1655, 1996. Apparent inhibition of apoptosis by polyamines and aminothiols in DNA fragmentation assays is artifactual. Cell Death and Differentiation 3:323-330, 1996. Studies in red blood cell preservation 3. A phosphate-ammonium-adenine solution. Vox Sanguinis 58:94-99, 1990. -------------------------------------------------------------------------------- Chapters from Books: Conformational membrane changes in genitourinary neooplasia. In: Cellular Pathobiology of Human Disease. pp. 245-270. Aromatase inhibitors. In: Biochemistry and Function of Sterols. Edward J. Parrish, Ph. D.,and W. D. Nes, Ph. D., eds. In press. -------------------------------------------------------------------------------- Invited Lectures: "Is Ploidy Prophetic?"
"Correlative
Microscopy" "Quantitation
in Pathology" |